New Posts New Posts RSS Feed - PGD
  FAQ FAQ  Forum Search   Events   Register Register  Login Login


Forum LockedPGD

 Post Reply Post Reply
Author
Alison View Drop Down
Groupie
Groupie


Joined: 20 May 2009
Points: 57
Post Options Post Options   Thanks (0) Thanks(0)   Quote Alison Quote  Post ReplyReply Direct Link To This Post Topic: PGD
    Posted: 20 May 2009 at 9:53pm
Hi, who has done PGD (Preimplantation Genetic Diagnosis)? My husband and I are investigating this, we have an appointment in July. There is a 50/50 chance that our offspring will be born with a hereditary heart condition which shows up later in life. We know which chromosome the mutation occurs in, am hoping in July they can tell us that they can test this specific mutation.

Wishing everyone well with there fertility journeys
Back to Top
Sponsored Links


Back to Top
AmyRay View Drop Down
Groupie
Groupie
Avatar

Joined: 18 March 2009
Location: Wellington
Points: 83
Post Options Post Options   Thanks (0) Thanks(0)   Quote AmyRay Quote  Post ReplyReply Direct Link To This Post Posted: 22 May 2009 at 8:41pm
Hi Alison,

I have just been through a publically funded cycle of IVF with PGD and actually started a thread on here called "IVF with PGD" if you want to have a look.
I think it is totally worth the effort as you have more of a chance of having a healthy baby without the abnormalities using the PGD. I have a chromosome translocation which means part of my genetic material is connected to another part and i only have a 50/50 chance of conceiving naturally. I started my cyle at the end of March. We had 12 eggs originally after EC (egg collection) and then after the cells had been tested at Monash in Australia, we found that we only had 3 eggs that had the right amount of chromosomes. Sadly only one made it to blatocyst stage so that egg was transferred at the end of April. I am 6 weeks pregnant today but have slow HCG rising levels so im not sure if things are going so well but will find out in my scan next Friday. But the positive thing is that we have got this far and know that the IVF with PGD works!!   
I no longer post to the "IVF with PGD" thread and have moved to the "First IVF cycle" thread as there are quite a few girls on there who are going through the same emotional feelings as me. These threads are a great idea and provide wonderful support.
Best of luck
Feel free to ask anymore questions you might have and i hope this was some help to you!!
26yrs old
TTC 5yrs
Endometriosis & Chromosomal Disorder
Natural Jun 07 - BFP but MC at 11.5 wks
IUI Jun 08 - BFP but MC at 11.5 wks
First IVF/PGD Cycle Mar 09 - BFP but MC at 6 wks
Back to Top
Alison View Drop Down
Groupie
Groupie


Joined: 20 May 2009
Points: 57
Post Options Post Options   Thanks (0) Thanks(0)   Quote Alison Quote  Post ReplyReply Direct Link To This Post Posted: 23 May 2009 at 12:15pm
Thank you so much AmyRay for your reply - it was very helpful and informative. Wishing you all the best for your scan next Friday, what an amazing story.

I feel like a fraud being on this forum, as we are able to conceive naturally and have a healthy 2 year old son. (All the genetic info has come to light after having him, and we have yet to decide when we are going to test his DNA for the mutation - it isn't life threatening at this stage of his life, but will still will mean lots of regular testing for him either way!). My husband has a pacemaker (at the age of 31) due to the genetic mutation. So now we are putting the brakes on trying for baby number 2 and investigating PGD.

Thanks again JavaScript:AddSmileyIcon('')
Back to Top
Alison View Drop Down
Groupie
Groupie


Joined: 20 May 2009
Points: 57
Post Options Post Options   Thanks (0) Thanks(0)   Quote Alison Quote  Post ReplyReply Direct Link To This Post Posted: 17 July 2009 at 3:13pm
Hi AmyRay, we had our appointment in Wellington a week ago now and had the PGD process explained, heard back from the nurse this week and Monash can screen for the genetic mutation that my husband has, it will take four months for them to create the test, so if we go head then possibly the start of next year we might be making a start. I JUST DON'T KNOW whether to do it, there are so many variables in out case, the main one been that we can conceive naturally but on the other hand this mutation causes sudden death through heart complications at an average age of 50!!!! Am not looking for an answer just looking for some where to vent my frustration, am ready to make a decision and get on with life.

Thanks for listening, Alison
Back to Top
AmyRay View Drop Down
Groupie
Groupie
Avatar

Joined: 18 March 2009
Location: Wellington
Points: 83
Post Options Post Options   Thanks (0) Thanks(0)   Quote AmyRay Quote  Post ReplyReply Direct Link To This Post Posted: 17 July 2009 at 4:02pm
Hi Alison, thats great that Monash can acutally screen for that. It really is a decision you have to make on your own though. Personally, i would give the IVF with PGD a try. At least you have a much higher chance of getting a healthy embryo without the heart condition which at the end of the day is ideally what you want. Will you have to fund this yourself, is this why you are apprehensive?? I know it is a lot of money. Our last cycle was funded but i know the costs for PGD are a lot higher than just a normal round of IVF.
Feel free to vent..... thats what we are here for!!!
26yrs old
TTC 5yrs
Endometriosis & Chromosomal Disorder
Natural Jun 07 - BFP but MC at 11.5 wks
IUI Jun 08 - BFP but MC at 11.5 wks
First IVF/PGD Cycle Mar 09 - BFP but MC at 6 wks
Back to Top
Alison View Drop Down
Groupie
Groupie


Joined: 20 May 2009
Points: 57
Post Options Post Options   Thanks (0) Thanks(0)   Quote Alison Quote  Post ReplyReply Direct Link To This Post Posted: 17 July 2009 at 9:35pm
Hi, we won't have to fund it ourselves, which is great.

How did you manage working and doing IVF? I work at an Childcare Centre, and am considering taking some leave while doing IVF (if we decide to!), just so I can give it my all. I get hormonal at the best of times, so have visions of me eating my colleagues alive!!! It's not like I work at an office desk and can hide! And how are those injections?
Back to Top
AmyRay View Drop Down
Groupie
Groupie
Avatar

Joined: 18 March 2009
Location: Wellington
Points: 83
Post Options Post Options   Thanks (0) Thanks(0)   Quote AmyRay Quote  Post ReplyReply Direct Link To This Post Posted: 20 July 2009 at 10:07am
Hi Alison,

I worked during most of the IVF process cos the whole thing takes about 6 weeks from start to finish. I took a week or so off during the egg collection process because we had to go up to Auckland to have that done. But in saying that, when i do my next cycle i am probably going to take 2-3 weeks off.

The injections arent too bad. You get used to them. Its a little bit painful towards the end as you are bloated and bruised but you get pretty good at it after a while!!!!!!!!!
26yrs old
TTC 5yrs
Endometriosis & Chromosomal Disorder
Natural Jun 07 - BFP but MC at 11.5 wks
IUI Jun 08 - BFP but MC at 11.5 wks
First IVF/PGD Cycle Mar 09 - BFP but MC at 6 wks
Back to Top
Alison View Drop Down
Groupie
Groupie


Joined: 20 May 2009
Points: 57
Post Options Post Options   Thanks (0) Thanks(0)   Quote Alison Quote  Post ReplyReply Direct Link To This Post Posted: 05 August 2009 at 8:11pm
So we have decided to go ahead with PGD, YEAH!!! Am so glad we have made the decision, our house hold seems to be flowing a whole lot better for it!!!! So are starting the feasibility side of the process in a couple of weeks - we get our blood taken and sent off to Monash. This is taking a bit of co-ordinating and working out logistics since we don't live in Wellies, then we just wait to see how long it takes Monash to create the test BRING IT ON

All the best AmyRay for you next cycle
Back to Top
mtjt View Drop Down
Senior Member
Senior Member


Joined: 05 January 2009
Location: tauranga BOP
Points: 266
Post Options Post Options   Thanks (0) Thanks(0)   Quote mtjt Quote  Post ReplyReply Direct Link To This Post Posted: 11 October 2009 at 5:59pm
Hi Alison and Amyray
Just reading bit about PGD.. what is it exactly? the reason is that im asking is i have just had my 2nd ivf/icsi round with another BFN our issue is DH sperm antibodies, however ICSI will over come this, but we dont seem to have any good embies?? they just dont divide properly??? I just wonder if PGD maybe an option for us and whats involved. I am hoping for another appointment with FA doctor to discuss our options... Any advice greatly appreciated

Edited by mtjt
Back to Top
Alison View Drop Down
Groupie
Groupie


Joined: 20 May 2009
Points: 57
Post Options Post Options   Thanks (0) Thanks(0)   Quote Alison Quote  Post ReplyReply Direct Link To This Post Posted: 11 October 2009 at 9:27pm
Hi mtjt

PGD (pre implantation genetic diagnosis) - our children have a 50/50 chance of being born with a gene mutation that causes heart problems, we have been able to identify what gene this is, so the process is that we go through IVF then once the embies have been removed they screen them to see which ones have the mutation and those that don't and hopefully one successfully doesn't and grows enough to be implanted. Fertility associates websites have a good run down on this process. We are hoping to start this process early next year! There is another website that has a good run down of the process when I find it I will post the link.

My thoughts are with you with news of your BFN

My unqulaified opinion would be that PGD is only helpful if you know exactly what part of your genetic's is causing the problem.

HOPE THIS HELPS, TAKE CARE ALISON

Edited by Alison
Back to Top
Alison View Drop Down
Groupie
Groupie


Joined: 20 May 2009
Points: 57
Post Options Post Options   Thanks (0) Thanks(0)   Quote Alison Quote  Post ReplyReply Direct Link To This Post Posted: 27 November 2009 at 12:11pm
YEAH we have a start date for our IVF/PGD cycle April 2010, am so grateful to have a date now, bring on 2010
Back to Top
karenm View Drop Down
Groupie
Groupie


Joined: 13 February 2009
Location: South Auckland
Points: 78
Post Options Post Options   Thanks (0) Thanks(0)   Quote karenm Quote  Post ReplyReply Direct Link To This Post Posted: 16 December 2009 at 5:37pm
[QUOTE=Alison] Hi mtjt

There is another website that has a good run down of the process when I find it I will post the link.

Alison - if you can, could you please post the link to the website. I am on a research mission.

Amyray - I have chromosome translocation too.   Did you do the PGD privately or was it via the public system? How are you doing?   
4 x m/c - Sep 08, Mar 09, Oct 09 & Feb 10
Back to Top
Alison View Drop Down
Groupie
Groupie


Joined: 20 May 2009
Points: 57
Post Options Post Options   Thanks (0) Thanks(0)   Quote Alison Quote  Post ReplyReply Direct Link To This Post Posted: 16 December 2009 at 7:37pm
here is the link I was referring to, this is off the Monash website which is the Australian company that the cells get sent to for testing during the IVF process. So at our current situation when reading the website link we are up to Step 4, in regards to step 3 our blood (DH, mine & our sons blood) got sent off to Monash and they have been able to create a test.

http://www.monashivf.com/default.asp?action=article&id=21857

and on this same website I saw them mention Chromosome Translocation so here is that link to . . .

http://www.monashivf.com/default.asp?action=article&ID=21858&KeyWords=PGD

Hope this helps
Back to Top
 Post Reply Post Reply

Forum Jump Forum Permissions View Drop Down

Forum Software by Web Wiz Forums® version 12.05
Copyright ©2001-2022 Web Wiz Ltd.

This page was generated in 1.000 seconds.