The phosphodiesterase-5 (PDE5) inhibitor tadalafil Toptada 20mg tablet is often used to treat erectile dysfunction.
Buy Toptada 20 drug can also be used to treat pulmonary hypertension, which is a kind of high blood pressure that affects the arteries in the lungs. Tadalafil acts by blocking the type 5 (PDE5) phosphodiesterase enzyme, which is responsible for smooth muscle metabolism of cyclic guanosine monophosphate (cGMP). The inhibition caused a spike in cGMP levels during sexual excitement, which resulted in smooth muscle relaxation and increased blood flow to the corpus cavernosum of the penis, resulting in an erection. Go at
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